Do you want to drive change for patients living with diabetes, obesity, cardiovascular disease, liver disease or other severe, chronic illnesses? Do you want to join a department with a mission to establish and apply state-of-the-art genomics and screening technologies to discover and validate novel therapeutic targets? Do you have a proven track record in lab automation?
Then this might be your defining moment. Apply today and join us for a life-changing career!
About Novo Nordisk Research Centre Oxford (NNRCO)
Novo Nordisk is a leading global healthcare company, founded in 1923 and headquartered in Denmark. We employ more than 50,000 people in 80 countries and market our products in around 170 countries.
Novo Nordisk Research Centre Oxford (NNRCO) is one of Novo Nordisk’s Global Drug Discovery research sites focused on biology and target discovery across the broad spectrum of cardiometabolic disease in Oxford, United Kingdom.
Our location in the heart of the University of Oxford medical campus enables two-way collaborations with some of the best medical scientists in the world. We use genetics, functional genomics, human-centric disease models and computational biology to develop an unparalleled understanding of cardiometabolic disease and deliver therapies that transform the lives of patients.
You can read more about Novo Nordisk Research Centre Oxford at:
Research Centre Oxford (novonordisk.com)
About the Department
The Department of Discovery Technologies and Genomics has as its mission to establish and apply state-of-the-art genomics and screening technologies to discover and validate novel therapeutic targets for cardiometabolic diseases using human-centric in vitro approaches. Ultimately, our aim is to identify targets and key biology to discover new disruptive therapeutics.
The department is led by Thomas Meek, and consists of specialists, staff scientists and post-doctoral scientists. We are a dedicated, collaborative team, working with a variety of advanced technologies, including high-throughput screening, high-content imaging, single-cell sequencing, CRISPR editing, functional genomics, proteomics, peptidomics, and statistical modelling. Together, we share a passion for translational research and a desire to discover new scientific paths to improve the lives of patients.
The Position
The Automation team within Discovery Technologies and Genomics department is expanding its capabilities for running high-throughput screens for target discovery by building an additional fully integrated automation suite comprising liquid handlers, acoustic dispenser, a high-content imaging system and additional technologies critical for running complex cell-based experimental workflows. We are seeking an experienced automation scientist/ specialist for developing, validating, and executing automation protocols to run HTS campaigns in in-vitro human cell models for novel target discovery. The role will continue to build on our aspirations for complete end-to-end digitalisation, from scheduling automation workflows to data analysis and insights.
As part of the automation team, you will have the opportunity to work in a collaborative environment with scientists working on liver biology, obesity, cardiovascular disease, skeletal muscle biology, technology specialists and our colleagues in computational biology and genetics.
Moreover, you will:
- Lead operations on technologically advanced integrated automation platforms where you will develop, validate and execute automation methods and multi-day/week workflows
- Lead execution of large-scale, arrayed phenotypic screens using siRNA, CRISPR, peptide or small molecule approaches in complex in vitro human cell models to identify the next novel drug targets for the company
- Develop walkaway automation protocols to maximise utilisation of the platform
- Work with third party vendors to ensure hardware and software integration as well as maintenance of laboratory automation
- Develop expertise to troubleshoot technical and hardware issues and rectify them
- Document operating procedures, develop backup process, maintain record of experimental procedures in the electronic lab notebook and train new users
Qualifications
We would like to hear from you if you fit any of the criteria we have listed below
- Scientific or engineering degree in Biological Sciences with experience working in laboratory automation settings using liquid handlers and automation scheduling software for running high-throughput cell-based or biochemical screens
- Experience using HighRes Biosolutions’ Cellario scheduling software, scripting language such as C# and programming language such as Python
- Advanced experience using Biomek i5 software and method writing using JavaScript or Visual Basic
- Experience transferring manual workflows into HTS technologies and knowledge in functional genomics is desirable
- Ability to interpret technical documents illustrating mechanical and electrical drawings and understand software/ network connections is desirable
Furthermore, we see that you have attention to detail, exceptional organizational and communication skills and the ability to work on projects in parallel. You hold a diligent attention to health and safety requirements, system cleanliness and maintenance. You are also a superior problem-solver and have the ability to understand complex biological systems. You are a team player and self-starter and are strongly motivated to explore new ideas and methods to drive innovation for the benefit of our patients.
Working at Novo Nordisk
At Novo Nordisk, we use our skills, dedication and ambition to help people with diabetes and chronic metabolic diseases. We offer the chance to be part of a truly global workplace, where passion and engagement are met with opportunities for professional and personal development.
Contact
For further information, please contact Asmita Agrawal [email protected]
Deadline
19th of March 2023
The Talent Acquisition team will engage with applicants on an ongoing basis, so don’t hesitate to apply!
We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.
At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.