To work within the group of Dr Jason Chin at the Laboratory of Molecular Biology (LMB), providing research support for a programme in synthetic genomics. This is a Wellcome Trust funded position to 31/12/23.
Main duties/ Key responsibilities:
- To undertake basic research by applying tools of computation and analysis to capture and interpret biological data.
- To perform a range of bioinformatics analysis that may include some but not necessarily all of:
o Long and short reads sequencing, optical genome mapping (library preparation, sequencing, and data analysis)
o Design and run genomic pipelines (DNA variants detection, ATAC-seq, Hi-C, Bisulfite sequencing)
o Design, assembly, and analysis of large extrachromosomal DNA constructs.
o Telomere-to-telomere chromosome assembly
o
In silico modelling of translational efficiency and mRNA splicing
o RNA-seq
- To present information on research progress and outcomes as appropriate.
- To conduct literature and database searches.
- To contribute to the production of research reports and publications.
- To ensure and maintain an efficient and tidy Laboratory.
To plan and manage your experimental work within the project along with your supervisor and other members of the project team.
To ensure the research is carried in accordance with good practice and in compliance with local polices and legal requirements.
To contribute to the smooth running of the research group, including the effective use of resources, training of others and taking responsibility for use of communal facilities.
Working relationships:
You will report to Dr Jason Chin. You will interact and collaborate with Postdoctoral Scientists, Research Support Staff and Students, not only in your Group, but also across the LMB and with external Groups (e.g. The Wellcome Sanger Institute) as necessary.